Bacterial recombinant L-asparaginases: properties, structure and anti-proliferative activity
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منابع مشابه
Invitro Anti-Bacterial and Anti-Oxidative Activity of GlycyrrhizaGlabra L. from North of Golestan Province
ABSTRACT Background and Objective: Glycyrrhizaglabra L. is one of the most widely used medicinal herbs in Golestan province that is known for its anti-inflammatory, carminative, antiviral, anti-infection and anti-ulcer properties in Iranian traditional medicine. This study aimed to assess the anti-bacterial and anti-oxidative activity of G. glabrafrom th...
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Bacterial L-asparaginases, which are widely used in the antitumor therapy, act only as homotetramers, because their active sites are located at the interface between the subunits of the enzyme. Since salt bridges substantially stabilize L-asparaginase tetramers, we have supposed that oligomerization of bacterial L-asparaginase is a high-avidity process. This assumption was proved by bioinformat...
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ژورنال
عنوان ژورنال: Biomeditsinskaya Khimiya
سال: 2015
ISSN: 2310-6905,2310-6972
DOI: 10.18097/pbmc20156103312